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Florinef is intended for:

Treating adrenocortical insufficiency in Addison disease and for treating salt-losing adrenogenital syndrome. Florinef is a corticosteroid. Florinef operates by causing the kidneys to retain sodium and acting as a replacement for cortisone when the body does not produce enough.

How to use Florinef:

Use Florinef as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Florinef by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Do not suddenly stop taking Florinef. You may have an increased risk of side effects. If you need to stop Florinef or add a new medicine, your doctor will gradually lower your dose.
• If you miss a dose of Florinef , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Florinef.

Possible side effects of Florinef:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

• Difficulty sleeping; dizziness or lightheadedness; headache; increased appetite; increased sweating; indigestion; nervousness.

Seek medical attention right away if any of these SEVERE side effects occur:

• Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; changes in menstrual periods; chest pain; eye pain or increased pressure in the eye; fever, chills, or sore throat; joint or bone pain; mood or mental changes (eg, depression); muscle pain or weakness; seizures; severe or persistent headache; severe or persistent nausea or vomiting; stomach pain or bloating; swelling of feet or legs; trouble sleeping; unusual weight gain or loss; vision changes; vomiting material that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider.

Proper storage of Florinef:

Store Florinef at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Florinef out of the reach of children and away from pets.