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Prometrium is used for:

Protecting the lining of the uterus in certain women who are also taking estrogen. It is used to treat certain women who have do not have a menstrual period because of decreased progesterone in the body. It may also be used for other conditions as determined by your doctor.
Prometrium is a hormone. It works by changing the lining of the uterus.

Do NOT use Prometrium if:

• you are allergic to any ingredient in Prometrium or to peanuts
• you have a history of cancer of the breast, ovary, lining of the uterus, cervix, or vagina; vaginal bleeding of unknown cause; blood clots or clotting problems; or liver disease; you have had a recent miscarriage; or you have had a stroke or heart attack within the past year
• you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Prometrium:

Some medical conditions may interact with Prometrium . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart or blood vessel problems, bleeding problems, high blood pressure, high cholesterol or lipid levels, diabetes, kidney problems, asthma, migraine headaches, or lupus
• if you have a history of seizures, depression or other mental or mood problems, cancer, or tobacco use
• if you have a family history of blood clots
• if you are very overweight

Some MEDICINES MAY INTERACT with Prometrium. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Rifampin because it may decrease Prometrium 's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Prometrium may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Prometrium:

Use Prometrium as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Prometrium . Talk to your pharmacist if you have questions about this information.
• Take Prometrium by mouth with or without food.
• If you miss a dose of Prometrium , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Prometrium.

Proper storage of Prometrium:

Store Prometrium at 77 degrees F (25 degrees C) in a tight, light-resistant container. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Prometrium out of the reach of children and away from pets.